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Which of the following are similarities between Cytochrome P450 and MAO?
Which of the following are similarities between Cytochrome P450 and MAO?
A . Both add oxygen from O2 to substrates and also form water
B . Both carry out direct heteroatom oxidations
C . Both carry out oxidative deaminations
D . Both carry out N-dealkylations
E . All of the above
Answer: C
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A five-year-old child presented with a three days history of nocturnal cough, wheezing and difficulty breathing. Examinations were unremarkable except for rhonchi on auscultation. A diagnosis of acute exacerbation of asthma-severity moderate was made.
A. List three drugs and their pharmacological classification that will be used in the acute management of this condition. (6 marks)
B. State the mechanism of action of any two of the drugs in (A). (5 marks)
C. Describe the pharmacokinetics of the two drugs stated in (B). (6 marks)
D. List two (2) medications that will be used in the long term management of this condition. (2 marks)
E. State three (3) side effects of the two drugs stated in (B). (6 marks)
(Kindly provide medications that work mainly on the respiratory system)