What would happen to theophylline clearance for an asthmatic patient in hospital who could not smoke?

FPGEE 1 Comment

Cigarette smoke causes an increase in levels of CYP1A isozymes. Theophylline is primarily metabolized by the CYP1A system.

What would happen to theophylline clearance for an asthmatic patient in hospital who could not smoke?
A . No change
B . Increase
C . Decrease

Answer: C

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Belachew Weldegebriel Gebremariam
Belachew Weldegebriel Gebremariam
1 year ago

I can’t understand why it decreases. In my opinion the answer should be A.

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