Which is the best agent to reduce the risk of pre-eclampsia in this patient?

A pregnant 36-year-old woman presented to the diabetes outpatient clinic. She had type 2 diabetes mellitus treated with diet, lifestyle changes and metformin 500 mg twice daily.

On examination, her blood pressure was 128/84 mmHg.

Investigations:

haemoglobin A1c47 mmol/mol (20C42)

urinary albumin: creatinine ratio1.6 mg/mmol (<3.5)

Which is the best agent to reduce the risk of pre-eclampsia in this patient?
A . aspirin
B . folic acid
C . insulin
D . labetalol
E . omega-3-marine triglycerides

Answer: A

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