What is the most appropriate investigation?

A 29-year-old lady who is a bank manager is referred by the GP to the medical OPC due to a long history of tin in the joints. An autoimmune screen result showed smooth muscle antibodies positive.

What is the most appropriate investigation?
A . Jejunal biopsy
B . Thyroid function test
C . Liver function test
D . Serum glucose
E . ECG

Answer: C

Explanation:

Autoimmune hepatitis. Definitive investigation is liver biopsy Steroid [start with high dose prednisolone]. Azathioprine is commonly added with steroid to reduce its dose as more side effects than azathioprine.