Serum amylase and lipase levels may be slightly elevated in chronic pancreatitis, but not diagnostic enough to predict chronic pancreatitis; wheras high levels are found only during acute pancreatitis episodes. In the later stages of chronic pancreatitis, normal to decreased levels of amylase and lipase are caused by the gradual inability of the pancreas to secrete the enzyme

Serum amylase and lipase levels may be slightly elevated in chronic pancreatitis, but not diagnostic enough to predict chronic pancreatitis; wheras high levels are found only during acute pancreatitis episodes. In the later stages of chronic pancreatitis, normal to decreased levels of amylase and lipase are caused by the gradual inability of the pancreas to secrete the enzyme

All of the statements below regarding amylase and lipase in pancreatitis are TRUE EXCEPT:
A . Amylase and lipase are as predictive in chronic as in acute pancreatitis.
B. Diagnosis sensitivity is increased by assaying both amylase and lipase.
C. Urinary amylase: creatinine ratio is the most sensitive test for acute pancreatitis.
D. Serum lipase peaks at 24 hours after an episode of acute pancreatitis and remains high for 7-8 days.s.

Answer: A

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